PDBsum entry 9q1v

De novo protein

PDB id: 9q1v

Contents

Protein chains

68 a.a.

164 a.a.

Waters ×236

PDB id:

9q1v

Name:

De novo protein

Title:

Crystal structure of de novo design fimh minibinder f7 complex

Structure:

Fimh minibinder f7. Chain: a, c. Engineered: yes. Type 1 fimbrin d-mannose specific adhesin. Chain: b, d. Synonym: protein fimh. Engineered: yes. Mutation: yes

Source:

Synthetic construct. Organism_taxid: 32630. Expressed in: escherichia coli. Expression_system_taxid: 562. Escherichia coli. Organism_taxid: 562. Gene: fimh, b4320, jw4283. Expression_system_taxid: 562

Resolution:

1.75Å R-factor: 0.234 R-free: 0.263

Authors:

A.K.Bera,A.Kang,T.Thomson,A.Chazin-Gray,D.Baker

Key ref:

A.M.Chazin-Gray et al. De novo design of miniprotein inhibitors of bacterial adhesins.. Biorxiv, . PubMed id: 40894640 DOI: 10.1101/2025.08.18.670751

Date:

14-Aug-25 Release date: 17-Sep-25

Protein chains

No UniProt id for this chain

Struc: 68 a.a.

Protein chains

P08191  (FIMH_ECOLI) -  Type 1 fimbrin D-mannose specific adhesin from Escherichia coli (strain K12)

Seq: 300 a.a.

Struc: 164 a.a.*

* PDB and UniProt seqs differ at 8 residue positions (black crosses)