PDBsum entry 9o4f

Viral protein

PDB id: 9o4f

Contents

Protein chains

360 a.a.

155 a.a.

Ligands

NAG-NAG-BMA-MAN-MAN ×3

NAG-NAG ×9

NAG-NAG-BMA ×9

NAG-NAG-BMA-FUC ×3

NAG ×6

PDB id:

9o4f

Name:

Viral protein

Title:

Pre-fusion stabilized herv-k envelope trimer ectodomain

Structure:

Surface protein. Chain: a, b, c. Synonym: su. Engineered: yes. Mutation: yes. Other_details: phoenix consensus sequence (dewannieux, marie, et al. 2006). Engineered v437c mutation. Transmembrane protein,fibritin. Chain: d, e, f.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ervk-6, ervk6. Expressed in: drosophila melanogaster. Expression_system_taxid: 7227. Expression_system_cell_line: s2. Expression_system_atcc_number: crl-1963. Homo sapiens, enterobacteria phage t4.

Authors:

J.Shek,C.Sun,K.Hastie,E.O.Saphire

Key ref:

J.Shek et al. Human endogenous retrovirus k (herv-K) envelope struc in pre- And post-Fusion by cryo-Em. To be published, . PubMed id: 40864726

Date:

08-Apr-25 Release date: 30-Jul-25

Protein chains

Q69384  (ENK6_HUMAN) -  Endogenous retrovirus group K member 6 Env polyprotein from Homo sapiens

Seq: 699 a.a.

Struc: 360 a.a.*

Protein chains

P10104  (WAC_BPT4) -  Fibritin from Enterobacteria phage T4

Seq: 487 a.a.

Struc: 155 a.a.*

Protein chains

Q69384  (ENK6_HUMAN) -  Endogenous retrovirus group K member 6 Env polyprotein from Homo sapiens

Seq: 699 a.a.

Struc: 155 a.a.*

* PDB and UniProt seqs differ at 137 residue positions (black crosses)