PDBsum entry 9mef

Immune system

PDB id: 9mef

Contents

Protein chains

264 a.a.

100 a.a.

Ligands

ARG-ALA-PHE-PRO-LYS-LYS-LYS-TYR-CYS-LEU

Waters ×300

PDB id:

9mef

Name:

Immune system

Title:

Conformational flexibility in hla-b8: peptide tuning structural and dynamical changes

Structure:

Mhc class i protein. Chain: a. Engineered: yes. Beta-2-microglobulin. Chain: b. Fragment: unp residues 21-119. Engineered: yes. Arg-ala-arg-ala-arg-ala-arg-ala-arg-ala-arg-ala-phe-pro- lys-lys-lys-tyr-cys-leu.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: b2m, cdabp0092, hdcma22p. Synthetic: yes. Human immunodeficiency virus 1.

Resolution:

1.27Å R-factor: 0.198 R-free: 0.227

Authors:

L.Li,M.Bouvier

Key ref:

L.Li et al. Conformational flexibility in hla-B8: peptide tuning structural and dynamical changes. To be published, .

Date:

06-Dec-24 Release date: 10-Dec-25

Protein chain

A0A3G6II09  () -  MHC class I protein (Fragment) from Homo sapiens

Seq: 312 a.a.

Struc: 264 a.a.*

Protein chain

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 100 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)