PDBsum entry 9j0s

Oxidoreductase

PDB id: 9j0s

Contents

Protein chains

452 a.a.

Ligands

NAP ×4

Waters ×72

PDB id:

9j0s

Name:

Oxidoreductase

Title:

Crystal structure of a novel aldehyde dehydrogenase from klebsiella pneumoniae with ligand

Structure:

Aldehyde dehydrogenase. Chain: a, b, c, d. Synonym: aldehyde dehydrogenase family protein,putative aldehyde dehydrogenase. Engineered: yes. Other_details: sequence reference for klebsiella pneumoniae (573) is not available in uniprot at the time of biocuration. Current sequence reference is from uniprot id a0a069q1d5.

Source:

Klebsiella pneumoniae. Organism_taxid: 573. Gene: yfmt, xylc_1, caz10_02010, dt376_04100, ipc1295_07430, nctc13621_03651, paerug_p19_london_7_vim_2_05_10_05035. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768

Resolution:

2.88Å R-factor: 0.210 R-free: 0.260

Authors:

J.Zhang,Y.Han,W.D.Liu,W.Y.Zhang

Key ref:

Y.Han et al. (2025). Aldehyde dehydrogenase from klebsiella pneumoniae: a biocatalyst for preparing heteroatom-Containing carbo acids. Adv.Synth.Catal., 367, . DOI: 10.1002/ADSC.202500027

Date:

02-Aug-24 Release date: 30-Jul-25

Protein chains

A0A069Q1D5  () -  Aldehyde dehydrogenase from Pseudomonas aeruginosa

Seq: 489 a.a.

Struc: 452 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.1.2.1.3,1.2.1.28 - aldehyde dehydrogenase (NAD(+)).
• Reaction: an aldehyde + NAD⁺ + H2O = a carboxylate + NADH + 2 H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site