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PDBsum entry 9hg0
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Oxidoreductase
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PDB id
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9hg0
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PDB id:
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| Name: |
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Oxidoreductase
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Title:
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Crystal structure of m. Smegmatis gmp reductase with xmp Intermidiate in complex with NADP+ and imp.
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Structure:
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Gmp reductase. Chain: a, b, c, d, e, f, g, h. Synonym: guanosine 5'-monophosphate reductase,gmpr. Engineered: yes
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Source:
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Mycolicibacterium smegmatis. Organism_taxid: 1772. Strain: atcc 700084 / mc(2)155. Gene: guab1, msmeg_3634, msmei_3548. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Resolution:
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2.10Å
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R-factor:
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0.220
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R-free:
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0.249
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Authors:
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M.Dolezal,I.Pichova
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Key ref:
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M.Dolezal
et al.
Structural basis for allosteric regulation of mycobac guanosine 5'-Monophosphate reductase with ATP and gtp.
To be published,
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Date:
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18-Nov-24
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Release date:
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27-Aug-25
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PROCHECK
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Headers
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References
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A0QYE8
(A0QYE8_MYCS2) -
GMP reductase from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
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Seq:
Struc:
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478 a.a.
473 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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Enzyme class:
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E.C.1.7.1.7
- Gmp reductase.
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Reaction:
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IMP + NH4+ + NADP+ = GMP + NADPH + 2 H+
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IMP
Bound ligand (Het Group name = )
corresponds exactly
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+
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NH4(+)
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+
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NADP(+)
Bound ligand (Het Group name = )
corresponds exactly
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=
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GMP
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+
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NADPH
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+
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2
×
H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
