PDBsum entry 9fns

Viral protein

PDB id: 9fns

Contents

Protein chains

143 a.a.

121 a.a.

100 a.a.

Ligands

NAG ×2

PDB id:

9fns

Name:

Viral protein

Title:

Cryo-em structure of the p domain of the hepatitis e virus orf2 protein in complex with fab es1.327

Structure:

Secreted protein orf2. Chain: a, b. Synonym: orf2s. Engineered: yes. Human igg antibody es1.327 - fab heavy chain. Chain: c, e. Engineered: yes. Human igg antibody es1.327 - fab light chain. Chain: d, f.

Source:

Hepatitis e virus. Organism_taxid: 291484. Gene: orf2. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293. Homo sapiens. Organism_taxid: 9606. Expression_system_cell_line: hek293

Authors:

E.Baquero,L.Molinos,H.Mouquet

Key ref:

L.Molinos et al. Structural basis for the neutralization of hepatitis by human monoclonal antibodies. To be published, .

Date:

11-Jun-24 Release date: 14-May-25

Protein chains

Q9YLQ9  (CAPSD_HEVUS) -  Pro-secreted protein ORF2 from Hepatitis E virus genotype 3 (isolate Human/United States/US2)

Seq: 660 a.a.

Struc: 143 a.a.*

Protein chains

No UniProt id for this chain

Struc: 121 a.a.

Protein chains

No UniProt id for this chain

Struc: 100 a.a.

* PDB and UniProt seqs differ at 4 residue positions (black crosses)