PDBsum entry 9fb8

DNA binding protein

PDB id: 9fb8

Contents

Protein chain

418 a.a.

Ligands

ANP

O0J ×2

DMS

Metals

_MG

Waters ×377

PDB id:

9fb8

Name:

DNA binding protein

Title:

Xchem refined pif1-x0076 complex

Structure:

Atp-dependent DNA helicase pif1. Chain: a. Synonym: DNA repair and recombination helicase pif1,pif1/rrm3 DNA helicase-like protein. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: pif1, c15orf20. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.73Å R-factor: 0.173 R-free: 0.211

Authors:

B.D.Bax,A.A.Antson,C.M.Sanders,J.Brandao-Neto

Key ref:

C.M.Sanders and b.d.bax Structure-Based discovery of first on-Target inhibito the human pif1 helicase. To be published, . PubMed id: 39417423

Date:

12-May-24 Release date: 18-Sep-24

Protein chain

Q9H611  (PIF1_HUMAN) -  ATP-dependent DNA helicase PIF1 from Homo sapiens

Seq: 641 a.a.

Struc: 418 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.5.6.2.3 - Dna 5'-3' helicase.