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PDBsum entry 9faj
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protein ligands metals Protein-protein interface(s) links
Membrane protein PDB id
9faj

 

 

 

 

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Contents
Protein chains
356 a.a.
345 a.a.
352 a.a.
33 a.a.
193 a.a.
121 a.a.
Ligands
NAG-NAG-BMA-MAN-
MAN-MAN-MAN-MAN-
MAN-MAN
NAG-NAG-BMA ×2
NAG-NAG-BMA-MAN-
MAN-MAN ×3
NAG-NAG
PIO ×2
PGW ×5
D10 ×12
PX2 ×5
ABU ×2
R16 ×4
HEX
PLM ×5
OLC
CLR
Metals
_CL
Waters ×104
PDB id:
9faj
Name: Membrane protein
Title: Cryoem structure of human full-length alpha1beta3gamma2 gaba(a) receptor in complex with garlh4, the tmd of neuroligin2, gaba and megabody38, in a desensitised state (stated1)
Structure: Gamma-aminobutyric acid receptor subunit alpha-1. Chain: a, d. Synonym: gaba(a) receptor subunit alpha-1,gabaar subunit alpha-1. Engineered: yes. Gamma-aminobutyric acid receptor subunit beta-3. Chain: b, e. Synonym: gaba(a) receptor subunit beta-3,gabaar subunit beta-3. Engineered: yes. Isoform 2 of gamma-aminobutyric acid receptor subunit
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gabra1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293s-tetr. Expression_system_atcc_number: crl-1573. Expression_system_organ: kidney.
Authors: V.B.Kasaragod,A.R.Aricescu
Key ref: V.B.Kasaragod and a.r.aricescu Cryoem structure of human full-Length alpha1beta3gamm gaba(a) receptor in complex with garlh4, The tmd of neuroligin2, Gaba and megabody38, In a desensitised s (stated1). To be published, .
Date:
10-May-24     Release date:   02-Jul-25    
PROCHECK
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 Headers
 References

Protein chains
P14867  (GBRA1_HUMAN) -  Gamma-aminobutyric acid receptor subunit alpha-1 from Homo sapiens
Seq:
Struc: 		456 a.a.
356 a.a.
Protein chains
P28472  (GBRB3_HUMAN) -  Gamma-aminobutyric acid receptor subunit beta-3 from Homo sapiens
Seq:
Struc: 		473 a.a.
345 a.a.
Protein chain
P18507  (GBRG2_HUMAN) -  Gamma-aminobutyric acid receptor subunit gamma-2 from Homo sapiens
Seq:
Struc: 		475 a.a.
352 a.a.*
Protein chain
Q8NFZ4  (NLGN2_HUMAN) -  Neuroligin-2 from Homo sapiens
Seq:
Struc: 		 
Seq:
Struc: 		835 a.a.
33 a.a.
Protein chain
Q7Z7J7  (LHPL4_HUMAN) -  LHFPL tetraspan subfamily member 4 protein from Homo sapiens
Seq:
Struc: 		247 a.a.
193 a.a.
Protein chains
No UniProt id for this chain
Struc: 121 a.a.
Key:    Secondary structure
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 

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