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PDBsum entry 9f1v
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Immune system
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PDB id
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9f1v
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PDB id:
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| Name: |
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Immune system
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Title:
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Crystal structure of borrelia burgdorferi cspz-ya
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Structure:
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Complement regulator-acquiring surface protein 2 (crasp-2). Chain: a. Engineered: yes. Mutation: yes. Other_details: the first 4 residues (gamg) are remnants from the expression tag. There are two mutations introduced - tyr207ala and tyr211ala.
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Source:
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Borreliella burgdorferi b31. Organism_taxid: 224326. Gene: cspz, bb_h06. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Resolution:
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1.90Å
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R-factor:
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0.190
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R-free:
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0.241
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Authors:
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K.Brangulis,J.Malfetano,A.L.Marcinkiewicz,A.Wang,Y.-L.Chen,X.Yang, W.Lee,M.-E.Bottazzi,U.Pal,C.-L.Hsieh,W.-H.Chen,Y.-P.Lin
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Key ref:
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K.Brangulis
et al.
(2025).
Mechanistic insights into the structure-Based design cspz-Targeting lyme disease vaccine..
Nat commun,
16,
2898.
PubMed id:
DOI:
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Date:
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20-Apr-24
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Release date:
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16-Apr-25
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PROCHECK
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Headers
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References
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O50665
(O50665_BORBU) -
Complement regulator-acquiring surface protein 2 (CRASP-2) from Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
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Seq:
Struc:
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236 a.a.
217 a.a.*
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Key: |
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Secondary structure |
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*
PDB and UniProt seqs differ
at 3 residue positions (black
crosses)
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Links
