PDBsum entry 9cpm

Metal binding protein

PDB id: 9cpm

Contents

Protein chain

428 a.a.

Ligands

GOL ×4

Metals

_CU ×5

Waters ×477

PDB id:

9cpm

Name:

Metal binding protein

Title:

Thermus thermophilus hb27 laccase (tth-lac) mutant with partial deletion of beta-hairpin sequence

Structure:

Laccase. Chain: a. Engineered: yes. Mutation: yes

Source:

Thermus thermophilus hb27. Organism_taxid: 262724. Gene: tt_c1370. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008

Resolution:

1.60Å R-factor: 0.155 R-free: 0.182

Authors:

J.Lee,B.Miranda-Zaragoza,C.Rodriguez-Almazan,N.C.J.Strynadka

Key ref:

B.Miranda-Zaragoza et al. (2025). Structure-Function relationship of the beta-Hairpin o thermus thermophilus hb27 laccase.. Int j mol sci, 26, . PubMed id: 39859450 DOI: 10.3390/IJMS26020735

Date:

18-Jul-24 Release date: 05-Feb-25

Protein chain

Q72HW2  (Q72HW2_THET2) -  Laccase from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)

Seq: 462 a.a.

Struc: 428 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.1.10.3.2 - laccase.
• Reaction: 4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O
• Cofactor: Cu cation

Molecule diagrams generated from .mol files obtained from the KEGG ftp site