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PDBsum entry 9cmu
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PDB id:
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Hydrolase
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Title:
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Room-temperature x-ray structure of sars-cov-2 main protease drug resistant mutant (l50f, e166v) in complex with ensitrelvir (esv)
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Structure:
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3c-like proteinase nsp5. Chain: a. Synonym: 3cl-pro,3clp,main protease,mpro,non-structural protein 5, nsp5,sars coronavirus main proteinase. Engineered: yes
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Source:
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Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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2.00Å
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R-factor:
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0.161
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R-free:
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0.202
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Authors:
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A.Kovalevsky,L.Coates,O.Gerlits
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Key ref:
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A.Kovalevsky
et al.
Effects of sars-Cov-2 main protease mutations at posi l50, E166, And l167 rendering resistance to covalent noncovalent inhibitors..
J med chem,
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PubMed id:
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Date:
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15-Jul-24
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Release date:
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16-Oct-24
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PROCHECK
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Headers
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References
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Links
