PDBsum entry 9c8s

Ligase

PDB id: 9c8s

Contents

Protein chains

514 a.a.

Ligands

WTA ×3

PDB id:

9c8s

Name:

Ligase

Title:

Cryoem structure of cryptococcus neoformans h99 acetyl-coa synthetase in complex with adenosine-5'-ethylphosphate

Structure:

Acetyl-coenzyme a synthetase. Chain: a, b, c. Engineered: yes

Source:

Cryptococcus neoformans var. Grubii h99. Organism_taxid: 235443. Gene: cnag_00797. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008

Authors:

Z.Xu,N.J.Schnicker,A.J.Jezeski,D.J.Krysan

Key ref:

Z.Xu et al. Cryoem structure of cryptococcus neoformans h99 acety synthetase in complex with adenosine-5'-Ethylphosphat. To be published, .

Date:

12-Jun-24 Release date: 03-Jul-24

Protein chains

J9VFT1  (J9VFT1_CRYNH) -  Acetyl-coenzyme A synthetase from Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)

Seq: 680 a.a.

Struc: 514 a.a.

Enzyme reactions

• Enzyme class: E.C.6.2.1.1 - acetate--CoA ligase.
• Reaction: acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate

acetate + ATP + CoA = acetyl-CoA + AMP (Bound ligand (Het Group name = WTA) matches with 92.00% similarity) + diphosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site