PDBsum entry 9c7f

Immune system

PDB id: 9c7f

Contents

Protein chains

223 a.a.

211 a.a.

Ligands

PCA-PRO-ALA-ASP-GLY-ASN-PRO-ASP ×4

NAG-NAG-FUC ×4

Waters ×1414

PDB id:

9c7f

Name:

Immune system

Title:

Human monoclonal antibody mad24-01 bound to the n-terminus of cleaved circumsporozoite protein

Structure:

Monoclonal antibody mad24-01 fab heavy chain. Chain: h, a, c, e. Engineered: yes. Monoclonal antibody mad24-01 fab light chain. Chain: l, b, d, f. Engineered: yes. Circumsporozoite protein. Chain: q, g, i, j. Synonym: cs,pfcsp.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: cricetulus griseus. Expression_system_taxid: 10029. Synthetic: yes. Plasmodium falciparum 3d7. Organism_taxid: 36329

Resolution:

1.82Å R-factor: 0.212 R-free: 0.238

Authors:

R.Moskovitz,I.A.Wilson

Key ref:

C.Dacon et al. Protective antibodies target cryptic epitope unmasked cleavage of malaria sporozoite protein. Science, . PubMed id: 39745947

Date:

10-Jun-24 Release date: 25-Dec-24

Protein chains

No UniProt id for this chain

Struc: 223 a.a.

Protein chains

No UniProt id for this chain

Struc: 211 a.a.