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PDBsum entry 9bfs
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protein ligands Protein-protein interface(s) links
Signaling protein PDB id
9bfs

 

 

 

 

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Contents
Protein chains
1516 a.a.
Ligands
NAG-NAG-FUC ×2
NAG-NAG ×2
NAG ×16
PDB id:
9bfs
Name: Signaling protein
Title: Cryo-em structure of sevenless extracellular domain (dimer, ph 6.6)
Structure: Protein sevenless. Chain: a, b. Engineered: yes
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: sev, hd-265, cg18085. Expressed in: drosophila melanogaster. Expression_system_taxid: 7227
Authors: G.Cerutti,L.Shapiro
Key ref: G.Cerutti et al. (2024). Structures and ph-Dependent dimerization of the seven receptor tyrosine kinase.. Mol cell, 84, 4677. PubMed id: 39510067
Date:
18-Apr-24     Release date:   29-Jan-25    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
P13368  (7LESS_DROME) -  Protein sevenless from Drosophila melanogaster
Seq:
Struc: 		 
Seq:
Struc: 		 
Seq:
Struc: 		 
Seq:
Struc: 		 
Seq:
Struc: 		 
Seq:
Struc: 		2554 a.a.
1516 a.a.
Key:    Secondary structure

 Enzyme reactions 
   Enzyme class: E.C.2.7.10.1  - receptor protein-tyrosine kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
L-tyrosyl-[protein]
 + ATP
 = O-phospho-L-tyrosyl-[protein]
 +
ADP
Bound ligand (Het Group name = NAG)
matches with 41.38% similarity 		+ H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

 

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