PDBsum entry 8ygo

Hydrolase

PDB id: 8ygo

Contents

Protein chains

703 a.a.

150 a.a.

PDB id:

8ygo

Name:

Hydrolase

Title:

The complex by dsr2-ctd-spr with NAD

Structure:

Sir2-like domain-containing protein. Chain: a, b. Engineered: yes. Other_details: sequence reference for bacillus subtilis a29 (2508883) is not available in uniprot at the time of biocuration. Current sequence reference is from uniprot id d4g637.. Spr. Chain: c, d. Engineered: yes.

Source:

Bacillus subtilis a29. Organism_taxid: 2508883. Gene: bsnt_07056. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: b4122_1986, j5227_09585. Expression_system_taxid: 562

Authors:

X.Gao,H.Zhu,S.Cui

Key ref:

K.Zhu et al. (2025). Activation of the bacterial defense-Associated sirtui system.. Commun biol, 8, 297. PubMed id: 39994439 DOI: 10.1038/S42003-025-07743-3

Date:

26-Feb-24 Release date: 05-Mar-25

Protein chains

P0DXN8  (DSR2_BACIU) -  Defense-associated sirtuin 2 from Bacillus subtilis

Seq: 1005 a.a.

Struc: 703 a.a.

Protein chains

A0A162TY69  (A0A162TY69_BACIU) -  Uncharacterized protein from Bacillus subtilis

Seq: 264 a.a.

Struc: 150 a.a.

Enzyme reactions

• Enzyme class: Chains A, B: E.C.3.2.2.5 - NAD(+) glycohydrolase.
• Reaction: NAD⁺ + H2O = ADP-D-ribose + nicotinamide + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site