PDBsum entry 8vgo

Membrane protein/immune system

PDB id: 8vgo

Contents

Protein chains

225 a.a.

213 a.a.

165 a.a.

PDB id:

8vgo

Name:

Membrane protein/immune system

Title:

Cryoem structure of cd20 in complex with engineered conformationally rigid rituximab.4ds fab

Structure:

Rituximab.4ds fab heavy chain. Chain: a, h. Engineered: yes. Rituximab.4ds fab light chain. Chain: b, l. Engineered: yes. B-lymphocyte antigen cd20. Chain: g, i. Fragment: residues 41-297.

Source:

Homo sapiens. Organism_taxid: 9606. Expressed in: cricetulus griseus. Expression_system_taxid: 10029. Human. Gene: ms4a1, cd20. Expressed in: trichoplusia ni. Expression_system_taxid: 7111

Authors:

J.E.Kung,C.C.Jao,C.P.Arthur,J.Sudhamsu

Key ref:

J.E.Kung et al. Disulfide constrained fabs overcome target size limit for high-Resolution single-Particle cryo-Em.. Biorxiv, . PubMed id: 38798381

Date:

27-Dec-23 Release date: 06-Nov-24

Protein chains

No UniProt id for this chain

Struc: 225 a.a.

Protein chains

No UniProt id for this chain

Struc: 213 a.a.

Protein chains

P11836  (CD20_HUMAN) -  B-lymphocyte antigen CD20 from Homo sapiens

Seq: 297 a.a.

Struc: 165 a.a.