PDBsum entry 8v2c

Cytokine/receptor

PDB id: 8v2c

Contents

Protein chains

169 a.a.

198 a.a.

184 a.a.

Ligands

NAG-NAG ×5

NAG ×3

PDB id:

8v2c

Name:

Cytokine/receptor

Title:

Cryo-em structure of mouse type ii osm receptor complex: model for assembly core region

Structure:

Oncostatin-m. Chain: a. Engineered: yes. Interleukin-6 receptor subunit beta. Chain: b. Engineered: yes. Oncostatin-m-specific receptor subunit beta. Chain: c. Engineered: yes

Source:

Mus musculus. House mouse. Organism_taxid: 10090. Gene: osm. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: il6st. Expressed in: cricetulus griseus. Expression_system_taxid: 10029.

Authors:

Y.Zhou,M.C.Franklin

Key ref:

Y.Zhou et al. (2024). Structures of complete extracellular assemblies of ty and type ii oncostatin m receptor complexes.. Nat commun, 15, 9776. PubMed id: 39532904

Date:

22-Nov-23 Release date: 20-Nov-24

Protein chain

P53347  (ONCM_MOUSE) -  Oncostatin-M from Mus musculus

Seq: 263 a.a.

Struc: 169 a.a.

Protein chain

Q00560  (IL6RB_MOUSE) -  Interleukin-6 receptor subunit beta from Mus musculus

Seq: 917 a.a.

Struc: 198 a.a.

Protein chain

O70458  (OSMR_MOUSE) -  Oncostatin-M-specific receptor subunit beta from Mus musculus

Seq: 971 a.a.

Struc: 184 a.a.