PDBsum entry 8tnh

Viral protein/immune system

PDB id: 8tnh

Contents

Protein chains

453 a.a.

127 a.a.

125 a.a.

Ligands

NAG-NAG ×19

NAG-NAG-BMA

NAG-NAG-BMA-MAN ×2

NAG ×27

PDB id:

8tnh

Name:

Viral protein/immune system

Title:

Cryo-em structure of HIV-1 env bg505 ds-sosip in complex with broadly neutralizing llama nanobody g36 targeting the cd4-binding site

Structure:

HIV-1 bg505 ds-sosip gp120. Chain: a, c, e. Fragment: unp residues 30-505. Engineered: yes. HIV-1 bg505 ds-sosip gp41. Chain: b, d, f. Fragment: unp residues 509-661. Engineered: yes. Cd4-binding site nanobody g36.

Source:

Human immunodeficiency virus 1. Organism_taxid: 11676. Gene: env. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell: hek 293f. Lama glama. Llama. Organism_taxid: 9844.

Authors:

T.Zhou,P.D.Kwong,J.Xu

Key ref:

J.Xu and t.zhou Cryo-Em structure of HIV-1 env bg505 ds-Sosip in comp with broadly neutralizing llama nanobody g36 targetin cd4-Binding site. To be published, . PubMed id: 38704686

Date:

01-Aug-23 Release date: 08-May-24

Protein chains

Q2N0S6  (Q2N0S6_HV1) -  Envelope glycoprotein gp160 from Human immunodeficiency virus type 1

Seq: 860 a.a.

Struc: 453 a.a.*

Protein chains

Q2N0S6  (Q2N0S6_HV1) -  Envelope glycoprotein gp160 from Human immunodeficiency virus type 1

Seq: 860 a.a.

Struc: 127 a.a.*

Protein chains

No UniProt id for this chain

Struc: 125 a.a.

* PDB and UniProt seqs differ at 5 residue positions (black crosses)