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PDBsum entry 8t5c
Go to PDB code:
Viral protein/immune system
PDB id
8t5c
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Contents
Protein chains
202 a.a.
159 a.a.
116 a.a.
119 a.a.
109 a.a.
Ligands
NAG-NAG-BMA-MAN-
MAN-MAN-MAN-MAN
NAG-NAG-BMA
×4
NAG-BMA
×3
NAG-NAG-BMA-MAN-
MAN-MAN
×4
NAG-NAG-BMA-MAN-
MAN
×3
MAN-MAN-MAN
NAG
×23
PDB id:
8t5c
Links
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ProSAT
Name:
Viral protein/immune system
Title:
Lassa gpc trimer in complex with fab 8.11g and nanobody d5
Structure:
Glycoprotein g1. Chain: b, a, c. Synonym: gp1. Engineered: yes. Glycoprotein g2. Chain: b, a, c. Synonym: gp2. Engineered: yes. D5 nanobody.
Source:
Lassa virus josiah. Organism_taxid: 11622. Gene: gpc, gp-c. Expressed in: homo sapiens. Expression_system_taxid: 9606. Camelus bactrianus. Organism_taxid: 9837. Homo sapiens. Organism_taxid: 9606.
Authors:
J.Gorman,P.D.Kwong
Key ref:
J.Gorman and p.d.kwong Cleavage-Intermediate lassa virus trimer elicits neutralizing responses, Identifies neutralizing nanob and reveals an apex situated site-Of-Vulnerability.
To be published
, .
PubMed id:
38177144
Date:
13-Jun-23
Release date:
03-Jan-24
PROCHECK
Headers
References
Protein chains
?
P08669
(GLYC_LASSJ) - Pre-glycoprotein polyprotein GP complex from Lassa virus (strain Mouse/Sierra Leone/Josiah/1976)
Seq:
Struc:
491 a.a.
202 a.a.
*
Protein chains
?
P08669
(GLYC_LASSJ) - Pre-glycoprotein polyprotein GP complex from Lassa virus (strain Mouse/Sierra Leone/Josiah/1976)
Seq:
Struc:
491 a.a.
159 a.a.
*
Protein chain
No UniProt id for this chain
Struc:
116 a.a.
Protein chains
No UniProt id for this chain
Struc:
119 a.a.
Protein chains
No UniProt id for this chain
Struc:
109 a.a.
Key:
PfamA domain
Secondary structure
*
PDB and UniProt seqs differ at 6 residue positions (black crosses)
Links
