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PDBsum entry 8swf

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protein Protein-protein interface(s) links
Immune system PDB id
8swf

 

 

 

 

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Contents
Protein chains
(+ 2 more) 836 a.a.
PDB id:
8swf
Name: Immune system
Title: Cryo-em structure of nlrp3 open octamer
Structure: Nacht, lrr and pyd domains-containing protein 3. Chain: a, b, c, d, e, f, g, h. Synonym: angiotensin/vasopressin receptor aii/avp-like,caterpiller protein 1.1,clr1.1,cold-induced autoinflammatory syndrome 1 protein, cryopyrin,pyrin-containing apaf1-like protein 1. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: nlrp3, c1orf7, cias1, nalp3, pypaf1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
Authors: X.Yu,R.E.Matico,R.Miller,B.V.Schoubroeck,K.Grauwen,J.Suarez, B.Pietrak,N.Haloi,Y.Yin,G.J.Tresadern,L.Perez-Benito,E.Lindahl, A.Bottelbergs,D.Oehlrich,N.V.Opdenbosch,S.Sharma
Key ref: X.Yu et al. Cryo-Em structures of nlrp3 reveal its self-Activatio mechanism. Nat commun, .
Date:
18-May-23     Release date:   14-Feb-24    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q96P20  (NLRP3_HUMAN) -  NACHT, LRR and PYD domains-containing protein 3 from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1036 a.a.
836 a.a.
Key:    PfamA domain  Secondary structure

 Enzyme reactions 
   Enzyme class: E.C.3.6.4.-  - ?????
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

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