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PDBsum entry 8swf
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Immune system
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PDB id
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8swf
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PDB id:
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Immune system
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Title:
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Cryo-em structure of nlrp3 open octamer
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Structure:
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Nacht, lrr and pyd domains-containing protein 3. Chain: a, b, c, d, e, f, g, h. Synonym: angiotensin/vasopressin receptor aii/avp-like,caterpiller protein 1.1,clr1.1,cold-induced autoinflammatory syndrome 1 protein, cryopyrin,pyrin-containing apaf1-like protein 1. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: nlrp3, c1orf7, cias1, nalp3, pypaf1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
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Authors:
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X.Yu,R.E.Matico,R.Miller,B.V.Schoubroeck,K.Grauwen,J.Suarez, B.Pietrak,N.Haloi,Y.Yin,G.J.Tresadern,L.Perez-Benito,E.Lindahl, A.Bottelbergs,D.Oehlrich,N.V.Opdenbosch,S.Sharma
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Key ref:
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X.Yu
et al.
Cryo-Em structures of nlrp3 reveal its self-Activatio mechanism.
Nat commun,
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Date:
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18-May-23
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Release date:
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14-Feb-24
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PROCHECK
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Headers
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References
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Q96P20
(NLRP3_HUMAN) -
NACHT, LRR and PYD domains-containing protein 3 from Homo sapiens
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Seq: Struc:
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1036 a.a.
836 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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}
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