PDBsum entry 8svk

Apoptosis

PDB id: 8svk

Contents

Protein chains

74 a.a.

Ligands

PEG ×3

PGE ×3

PG4

SO4

Waters ×20

PDB id:

8svk

Name:

Apoptosis

Title:

Crystal structure of bax d71n core domain bh3-groove dimer

Structure:

Apoptosis regulator bax. Chain: a, b, c, d. Synonym: bcl-2-like protein 4,bcl2-l-4. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: bax, bcl2l4. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.25Å R-factor: 0.256 R-free: 0.287

Authors:

M.S.Miller,P.E.Czabotar,P.M.Colman

Key ref:

M.S.Miller et al. Sequence differences between bax and bak core domains manifest as differences in their interactions with li. Febs j, . PubMed id: 38088212

Date:

16-May-23 Release date: 27-Dec-23

Protein chains

Q07812  (BAX_HUMAN) -  Apoptosis regulator BAX from Homo sapiens

Seq: 192 a.a.

Struc: 74 a.a.*

* PDB and UniProt seqs differ at 3 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.?