PDBsum entry 8sir

Immune system

PDB id: 8sir

Contents

Protein chains

195 a.a.

226 a.a.

211 a.a.

Ligands

NAG

PDB id:

8sir

Name:

Immune system

Title:

Crystal structure of sars-cov-2 spike receptor-binding domain in complex with broadly neutralizing antibody cc25.54 fab

Structure:

Spike protein s1. Chain: a. Fragment: receptor binding domain, unp residues 333-530. Engineered: yes. Cc25.54 fab heavy chain. Chain: h. Engineered: yes. Cc25.54 fab light chain. Chain: l.

Source:

Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Homo sapiens. Human. Organism_taxid: 9606. Expressed in: mus musculus.

Resolution:

3.30Å R-factor: 0.209 R-free: 0.236

Authors:

H.Liu,I.A.Wilson

Key ref:

G.Song et al. Broadly neutralizing antibodies targeting a conserved face of spike rbd resist extreme sars-Cov-2 antigenic. Biorxiv, . PubMed id: 40627497

Date:

16-Apr-23 Release date: 13-Mar-24

Protein chain

P0DTC2  (SPIKE_SARS2) -  Spike glycoprotein from Severe acute respiratory syndrome coronavirus 2

Seq: 1273 a.a.

Struc: 195 a.a.

Protein chain

No UniProt id for this chain

Struc: 226 a.a.

Protein chain

No UniProt id for this chain

Struc: 211 a.a.