PDBsum entry 8s6m

Viral protein

PDB id: 8s6m

Contents

Protein chains

221 a.a.

196 a.a.

211 a.a.

214 a.a.

215 a.a.

Ligands

EDO ×9

NAG

TRS

Metals

_NI

Waters ×770

PDB id:

8s6m

Name:

Viral protein

Title:

Sars-cov-2 bq.1.1 rbd bound to the s2v29 and the s2h97 fab fragments

Structure:

S2v29 fab heavy chain. Chain: h. Engineered: yes. Spike protein s1. Chain: r. Engineered: yes. S2h97 fab heavy chain. Chain: i. Engineered: yes.

Source:

Homo sapiens. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Gene: s, 2. Expression_system_taxid: 9606

Resolution:

1.67Å R-factor: 0.185 R-free: 0.203

Authors:

J.M.Errico,Y.J.Park,T.Rietz,N.Czudnochowski,J.C.Nix,E.Cameroni, D.Corti,G.Snell,A.D.Marco,D.Pinto,Seattle Structural Genomics Center For Infectious Disease (Ssgcid),D.Veesler

Key ref:

L.E.Rosen et al. A potent pan-Sarbecovirus neutralizing antibody resil epitope diversification.. Cell, . PubMed id: 39383863

Date:

28-Feb-24 Release date: 23-Oct-24

Protein chain

No UniProt id for this chain

Struc: 221 a.a.

Protein chain

P0DTC2  (SPIKE_SARS2) -  Spike glycoprotein from Severe acute respiratory syndrome coronavirus 2

Seq: 1273 a.a.

Struc: 196 a.a.*

Protein chain

No UniProt id for this chain

Struc: 211 a.a.

Protein chain

No UniProt id for this chain

Struc: 214 a.a.

Protein chain

No UniProt id for this chain

Struc: 215 a.a.

* PDB and UniProt seqs differ at 20 residue positions (black crosses)