PDBsum entry 8rnh

Immune system

PDB id: 8rnh

Contents

Protein chains

276 a.a.

100 a.a.

Ligands

GLU-GLU-ILE-GLU-ILE-THR-THR-HIS-PHE

PEG

EDO ×2

Waters ×241

PDB id:

8rnh

Name:

Immune system

Title:

Crystal structure of hla b 18:01 In complex with eeieitthf, an 9-mer epitope from influenza a

Structure:

Mhc class i antigen. Chain: a. Engineered: yes. RNA-directed RNA polymerase catalytic subunit. Chain: c. Synonym: polymerase basic protein 1,pb1,RNA-directed RNA polymerase subunit p1. Engineered: yes. Beta-2-microglobulin.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Influenza a virus (a/memphis/18/1978(h3n2)). Organism_taxid: 383579.

Resolution:

1.60Å R-factor: 0.203 R-free: 0.235

Authors:

L.D.Murdolo,J.Maddumaage,S.Gras

Key ref:

L.D.Murdolo et al. Crystal structure of hla b18:01 In complex with eeie an 9-Mer epitope from influenza a. To be published, . PubMed id: 38737448

Date:

10-Jan-24 Release date: 08-May-24

Protein chain

S6AU73  (S6AU73_HUMAN) -  MHC class I antigen from Homo sapiens

Seq: 362 a.a.

Struc: 276 a.a.

Protein chain

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 100 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: Chains : E.C.2.7.7.48 - RNA-directed Rna polymerase.
• Reaction: RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site