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PDBsum entry 8rm2
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PDB id:
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Transferase
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Title:
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Erk2 map kinase t188e mutant
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Structure:
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Mitogen-activated protein kinase 1. Chain: a. Synonym: map kinase 1,mapk 1,ert1,extracellular signal-regulated kinase 2,erk-2,map kinase isoform p42,p42-mapk,mitogen-activated protein kinase 2,map kinase 2,mapk 2. Engineered: yes
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Source:
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Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: mapk1, erk2, mapk, prkm1. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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1.55Å
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R-factor:
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0.202
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R-free:
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0.236
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Authors:
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O.Livnah,D.Gutman
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Key ref:
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O.Livnah
and
d.gutman
Erk2 map kinase t188e mutant.
To be published,
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Date:
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04-Jan-24
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Release date:
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15-Jan-25
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PROCHECK
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Headers
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References
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P63086
(MK01_RAT) -
Mitogen-activated protein kinase 1 from Rattus norvegicus
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Seq:
Struc:
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358 a.a.
347 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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Enzyme class:
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E.C.2.7.11.24
- mitogen-activated protein kinase.
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Reaction:
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1.
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L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
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2.
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L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H+
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L-seryl-[protein]
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+
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ATP
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=
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O-phospho-L-seryl-[protein]
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+
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ADP
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+
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H(+)
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L-threonyl-[protein]
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+
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ATP
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=
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O-phospho-L-threonyl-[protein]
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+
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ADP
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
