PDBsum entry 8ref

Immune system

PDB id: 8ref

Contents

Protein chains

276 a.a.

98 a.a.

Ligands

SER-VAL-LEU-ASN-ASP-ILE-LEU-ALA-ARG-LEU

PEG ×3

EDO ×4

Metals

_NA ×2

Waters ×139

PDB id:

8ref

Name:

Immune system

Title:

Crystal structure of hla b 13:01 In complex with svlndilarl, an 10-mer epitope from sars-cov-2 spike (s975-984)

Structure:

Hla class i histocompatibility antigen b alpha chain. Chain: a. Engineered: yes. Beta-2-microglobulin. Chain: b. Fragment: unp residues 21-119. Engineered: yes. Spike protein s2'. Chain: c.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-b. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Gene: b2m, cdabp0092, hdcma22p. Synthetic: yes. Severe acute respiratory syndrome coronavirus

Resolution:

1.90Å R-factor: 0.188 R-free: 0.221

Authors:

Y.M.Ahn,J.C.Maddumage,C.Szeto,S.Gras

Key ref:

Y.M.Ahn et al. The impact of sars-Cov-2 spike mutation on peptide presentation is hla allomorph-Specific. Curr res struct biol, . PubMed id: 38742159

Date:

11-Dec-23 Release date: 15-May-24

Protein chain

C5IYE8  (C5IYE8_HUMAN) -  HLA class I histocompatibility antigen B alpha chain from Homo sapiens

Seq: 362 a.a.

Struc: 276 a.a.

Protein chain

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 98 a.a.