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PDBsum entry 8qw0
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PDB id:
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Transferase
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Title:
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Human ndpk-c in complex with gdp
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Structure:
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Nucleoside diphosphate kinase 3. Chain: a, b, c, d, e, f, g, h, i, j, k, l. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: nme3. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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2.18Å
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R-factor:
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0.189
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R-free:
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0.229
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Authors:
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S.Werten,R.Amjadi,K.Scheffzek
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Key ref:
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R.Amjadi
et al.
(2024).
Mechanistic insights into substrate recognition of hu nucleoside diphosphate kinase c based on nucleotide-I structural changes.
Int j mol sci,
25,
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PubMed id:
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Date:
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18-Oct-23
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Release date:
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18-Sep-24
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PROCHECK
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Headers
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References
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Q13232
(NDK3_HUMAN) -
Nucleoside diphosphate kinase 3 from Homo sapiens
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Seq:
Struc:
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169 a.a.
151 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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Enzyme class:
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E.C.2.7.4.6
- nucleoside-diphosphate kinase.
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Reaction:
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1.
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a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP
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2.
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a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP
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ribonucleoside 5'-diphosphate
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+
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ATP
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=
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ribonucleoside 5'-triphosphate
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+
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ADP
Bound ligand (Het Group name = )
matches with 96.43% similarity
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2'-deoxyribonucleoside 5'-diphosphate
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+
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ATP
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=
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2'-deoxyribonucleoside 5'-triphosphate
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+
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ADP
Bound ligand (Het Group name = )
matches with 96.43% similarity
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
