PDBsum entry 8omc

Oxidoreductase

PDB id: 8omc

Contents

Protein chains

363 a.a.

Ligands

HEM ×2

Waters ×648

PDB id:

8omc

Name:

Oxidoreductase

Title:

Y345f/f347y/y389f variant of dye type peroxidase aa (dtpaa) from streptomyces lividans

Structure:

Deferrochelatase. Chain: a, b. Engineered: yes

Source:

Streptomyces lividans 1326. Organism_taxid: 1200984. Gene: sli_2602. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008

Resolution:

1.50Å R-factor: 0.162 R-free: 0.189

Authors:

M.Lucic,J.A.R.Worrall,M.A.Hough

Key ref:

M.Lucic et al. Y345f/f347y/y389f variant of dye type peroxidase aa ( from streptomyces lividans. To be published, . PubMed id: 38020392

Date:

31-Mar-23 Release date: 10-Apr-24

Protein chains

A0A7U9DT46  (A0A7U9DT46_STRLI) -  Deferrochelatase from Streptomyces lividans 1326

Seq: 420 a.a.

Struc: 363 a.a.*

* PDB and UniProt seqs differ at 3 residue positions (black crosses)

Enzyme reactions

• Enzyme class 1: E.C.1.11.1.- - ?????
• Enzyme class 2: E.C.4.98.1.1 - protoporphyrin ferrochelatase.
• Reaction: heme b + 2 H⁺ = protoporphyrin IX + Fe²⁺

heme b + 2 × H(+) = protoporphyrin IX (Bound ligand (Het Group name = HEM) matches with 97.67% similarity) + Fe(2+)

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site