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PDBsum entry 8j1h

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protein ligands Protein-protein interface(s) links
Membrane protein PDB id
8j1h

 

 

 

 

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Contents
Protein chains
589 a.a.
Ligands
9QM ×4
PDB id:
8j1h
Name: Membrane protein
Title: Agonist1 and ruthenium red bound state of mtrpv4
Structure: Transient receptor potential cation channel subfamily v member 4. Chain: c, d, b, a. Synonym: trpv4,osm-9-like trp channel 4,otrpc4,transient receptor potential protein 12,trp12,vanilloid receptor-like channel 2, vanilloid receptor-like protein 2,vanilloid receptor-related osmotically-activated channel,vr-oac. Engineered: yes
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trpv4, trp12, vrl2, vroac. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell: hek 293
Authors: W.X.Zhen,F.Yang
Key ref: W.Zhen et al. (2023). Structural basis of ligand activation and inhibition mammalian trpv4 ion channel.. Cell discov, 9, 70. PubMed id: 37429860
Date:
12-Apr-23     Release date:   09-Aug-23    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q9EPK8  (TRPV4_MOUSE) -  Transient receptor potential cation channel subfamily V member 4 from Mus musculus
Seq:
Struc:
 
Seq:
Struc:
871 a.a.
589 a.a.
Key:    PfamA domain  Secondary structure

 Enzyme reactions 
   Enzyme class: E.C.?
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 

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