PDBsum entry 8irr

Membrane protein

PDB id: 8irr

Contents

Protein chains

226 a.a.

338 a.a.

58 a.a.

128 a.a.

282 a.a.

Ligands

R5F

CLR ×3

Waters ×6

PDB id:

8irr

Name:

Membrane protein

Title:

Dopamine receptor d1r-gs-rotigotine complex

Structure:

Guanine nucleotide-binding protein g(s) subunit alpha isoforms short. Chain: a. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnb1. Gene: gng2. Lama glama. Organism_taxid: 9844.

Authors:

P.Xu,S.Huang,Y.Zhuang,C.Mao,Y.Zhang,Y.Wang,H.Li,Y.Jiang,Y.Zhang, H.E.Xu

Key ref:

P.Xu et al. Structural genomics of the human dopamine receptor sy. Cell res, . PubMed id: 37221270

Date:

19-Mar-23 Release date: 21-Jun-23

Protein chain

No UniProt id for this chain

Struc: 226 a.a.

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 338 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 58 a.a.

Protein chain

No UniProt id for this chain

Struc: 128 a.a.

Protein chain

P21728  (DRD1_HUMAN) -  D(1A) dopamine receptor from Homo sapiens

Seq: 446 a.a.

Struc: 282 a.a.