PDBsum entry 8igc

Apoptosis

PDB id: 8igc

Contents

Protein chains

154 a.a.

23 a.a.

Waters ×126

PDB id:

8igc

Name:

Apoptosis

Title:

Crystal structure of bak bound to bnip5 bh3

Structure:

Bcl-2 homologous antagonist/killer. Chain: a. Synonym: apoptosis regulator bak,bcl-2-like protein 7,bcl2-l-7. Engineered: yes. Mutation: yes. Protein bnip5. Chain: b. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: bak1, bak, bcl2l7, cdn1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606

Resolution:

1.70Å R-factor: 0.205 R-free: 0.226

Authors:

B.Ku,D.Lim

Key ref:

D.Lim et al. Crystal structure of bak bound to the bh3 domain of b noncanonical bh3 domain-Containing protein.. Proteins, . PubMed id: 37553948

Date:

20-Feb-23 Release date: 20-Sep-23

Protein chain

Q16611  (BAK_HUMAN) -  Bcl-2 homologous antagonist/killer from Homo sapiens

Seq: 211 a.a.

Struc: 154 a.a.*

Protein chain

P0C671  (CF222_HUMAN) -  Protein BNIP5 from Homo sapiens

Seq: 652 a.a.

Struc: 23 a.a.

* PDB and UniProt seqs differ at 2 residue positions (black crosses)