PDBsum entry 8hvw

Viral protein

PDB id: 8hvw

Contents

Protein chains

299 a.a.

Ligands

80I ×2

Waters ×53

PDB id:

8hvw

Name:

Viral protein

Title:

Crystal structure of sars-cov-2 main protease m49i mutant in complex with pf07304814

Structure:

3c-like proteinase nsp5. Chain: a, b. Synonym: 3cl-pro,3clp,main protease,mpro,non-structural protein 5, nsp5,sars coronavirus main proteinase. Engineered: yes

Source:

Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008

Resolution:

2.05Å R-factor: 0.212 R-free: 0.251

Authors:

X.F.Zou,J.Zhang,J.Li

Key ref:

X.F.Zou et al. Crystal structure of sars-Cov-2 main protease m49i mu complex with pf07304814. To be published, . PubMed id: 37532968

Date:

28-Dec-22 Release date: 17-Jan-24

Protein chains

P0DTD1  (R1AB_SARS2) -

Enzyme reactions

• Enzyme class: E.C.3.4.22.69 - Sars coronavirus main proteinase.