PDBsum entry 8hvl

Viral protein/inhibitor

PDB id: 8hvl

Contents

Protein chains

299 a.a.

Ligands

4WI ×2

Waters ×242

PDB id:

8hvl

Name:

Viral protein/inhibitor

Title:

Crystal structure of sars-cov-2 main protease m49i mutant in complex with pf07321332

Structure:

3c-like proteinase nsp5. Chain: a, b. Synonym: 3cl-pro,3clp,main protease,mpro,non-structural protein 5, nsp5,sars coronavirus main proteinase. Engineered: yes. Mutation: yes. Other_details: severe acute respiratory syndrome coronavirus 2

Source:

Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

1.45Å R-factor: 0.205 R-free: 0.230

Authors:

X.F.Zou,J.Zhang,J.Li

Key ref:

X.F.Zou et al. Crystal structure of sars-Cov-2 main protease m49i mu complex with pf07321332. To be published, . PubMed id: 37222536

Date:

27-Dec-22 Release date: 27-Dec-23

Protein chains

P0DTD1  (R1AB_SARS2) -

Enzyme reactions

• Enzyme class: E.C.3.4.22.69 - Sars coronavirus main proteinase.