PDBsum entry 8hrh

Immune system

PDB id: 8hrh

Contents

Protein chains

214 a.a.

218 a.a.

Ligands

A2G-GAL-SIA

N7P-ASP-THR-ARG

ALA

TRS

PEG ×7

GOL ×2

PRO

LPD

Waters ×213

PDB id:

8hrh

Name:

Immune system

Title:

Sn-131/1b2 anti-muc1 antibody with a glycopeptide

Structure:

Heavy chain of sn-131/1b2 antibody fab. Chain: a. Engineered: yes. Light chain of sn-131/1b2 antibody fab. Chain: b. Engineered: yes

Source:

Mus musculus. Organism_taxid: 10090. Expressed in: mus musculus. Expression_system_taxid: 10090. Expression_system_cell_line: hybridoma

Resolution:

2.07Å R-factor: 0.192 R-free: 0.227

Authors:

H.Wakui,C.Horidome,M.Yao,T.Ose,S.-I.Nishimura

Key ref:

H.Wakui et al. (2023). Structural and molecular insight into antibody recogn of dynamic neoepitopes in membrane tethered muc1 of pancreatic cancer cells and secreted exosomes.. Rsc chem biol, 4, 564. PubMed id: 37547453 DOI: 10.1039/D3CB00036B

Date:

15-Dec-22 Release date: 30-Aug-23

Protein chain

No UniProt id for this chain

Struc: 214 a.a.

Protein chain

No UniProt id for this chain

Struc: 218 a.a.