PDBsum entry 8hqy

Structural protein

PDB id: 8hqy

Contents

Protein chains

97 a.a.

83 a.a.

107 a.a.

91 a.a.

23 a.a.

74 a.a.

DNA/RNA

PDB id:

8hqy

Name:

Structural protein

Title:

Cryo-em structure of ssx1 bound to the h2ak119ub nucleosome at a resolution of 3.05 angstrom

Structure:

Histone h3. Chain: a, e. Engineered: yes. Histone h4 (fragment). Chain: b. Engineered: yes. Histone h2a type 1-b/e. Chain: c. Synonym: histone h2a.2,histone h2a/a,histone h2a/m.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: calmac_locus17614. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: n305_08114. Gene: h2ac4, h2afm, hist1h2ab, h2ac8, h2afa, hist1h2ae. Gene: h2bc12, h2bft, hirip1, hist1h2bk.

Authors:

T.Zebin,H.S.Ai,X.Ziyu,C.Guochao,P.Man,L.Liu

Key ref:

T.Zebin et al. A cryptic basic groove formed by ubiquitin and histon mediates selective recognition of h2ak119ub nucleosom synovial sarcoma X breakpoint 1 protein.. Nat struct mol biol, . PubMed id: 38177667

Date:

14-Dec-22 Release date: 27-Sep-23

Protein chains

Q71DI3  (H32_HUMAN) -  Histone H3.2 from Homo sapiens

Seq: 136 a.a.

Struc: 97 a.a.*

Protein chains

P62805  (H4_HUMAN) -  Histone H4 from Homo sapiens

Seq: 103 a.a.

Struc: 83 a.a.

Protein chains

P04908  (H2A1B_HUMAN) -  Histone H2A type 1-B/E from Homo sapiens

Seq: 130 a.a.

Struc: 107 a.a.*

Protein chains

O60814  (H2B1K_HUMAN) -  Histone H2B type 1-K from Homo sapiens

Seq: 126 a.a.

Struc: 91 a.a.

Protein chain

Q16385  (SSX2_HUMAN) -  Protein SSX2 from Homo sapiens

Seq: 188 a.a.

Struc: 23 a.a.

Protein chain

P0CG47  (UBB_HUMAN) -  Polyubiquitin-B from Homo sapiens

Seq: 229 a.a.

Struc: 74 a.a.

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

DNA/RNA chains

A-T-G-A-G-A-A-T-C-C-C-G-G-T-G-C-C-G-A-G-G-C-C-G-C-T-C-A-A-T-T-G-G-T-C-G-T-A-G- 136 bases

T-A-T-A-T-C-T-G-A-C-A-C-G-T-G-C-C-T-G-G-A-G-A-C-T-A-G-G-G-A-G-T-A-A-T-C-C-C-C- 136 bases