PDBsum entry 8hqg

Viral protein/inhibitor

PDB id: 8hqg

Contents

Protein chains

298 a.a.

Ligands

HUR ×2

Waters ×75

PDB id:

8hqg

Name:

Viral protein/inhibitor

Title:

Crystal structure of sars-cov-2 main protease k90r mutant in complex with inhibitor yh-53

Structure:

3c-like proteinase nsp5. Chain: a, b. Synonym: 3cl-pro,3clp,main protease,mpro,non-structural protein 5, nsp5,sars coronavirus main proteinase. Engineered: yes. Mutation: yes

Source:

Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

1.88Å R-factor: 0.218 R-free: 0.264

Authors:

J.Wang,J.Zhang,J.Li

Key ref:

J.Wang et al. Crystal structure of sars-Cov-2 main protease k90r mu complex with inhibitor yh-53. To be published, . PubMed id: 37357528

Date:

13-Dec-22 Release date: 20-Dec-23

Protein chains

P0DTD1  (R1AB_SARS2) -

Enzyme reactions

• Enzyme class: E.C.3.4.22.69 - Sars coronavirus main proteinase.