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PDBsum entry 8hpp

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protein Protein-protein interface(s) links
Transcription PDB id
8hpp

 

 

 

 

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Contents
Protein chains
395 a.a.
86 a.a.
PDB id:
8hpp
Name: Transcription
Title: Crystal structure of human ints3 with sage1
Structure: Integrator complex subunit 3. Chain: a, b. Fragment: c-terminal motif. Synonym: int3,soss complex subunit a,sensor of single-strand DNA complex subunit a,soss-a,sensor of ssdna subunit a. Engineered: yes. Sarcoma antigen 1. Chain: c. Synonym: cancer/testis antigen 14,ct14.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ints3, c1orf193, c1orf60. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: sage1, sage.
Resolution:
3.00Å     R-factor:   0.217     R-free:   0.257
Authors: W.Deng,J.Wu,M.Lei
Key ref: W.Deng et al. Cancer-Testis antigen sage1 is a pan-Cancer master re of RNA polymerase ii. To be published, .
Date:
12-Dec-22     Release date:   20-Dec-23    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q68E01  (INT3_HUMAN) -  Integrator complex subunit 3 from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1043 a.a.
395 a.a.
Protein chain
Pfam   ArchSchema ?
Q9NXZ1  (SAGE1_HUMAN) -  Sarcoma antigen 1 from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
904 a.a.
86 a.a.*
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 

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