PDBsum entry 8hk3

Membrane protein

PDB id: 8hk3

Contents

Protein chains

223 a.a.

339 a.a.

284 a.a.

56 a.a.

233 a.a.

PDB id:

8hk3

Name:

Membrane protein

Title:

C3ar-gi-apo protein complex

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Rattus norvegicus. Norway rat. Organism_taxid: 10116.

Authors:

Y.Wang,W.Liu,Y.Xu,Y.Zhuang,H.E.Xu

Key ref:

Y.Wang et al. Illumination of the complement receptors c3ar and c5a signaling by anaphylatoxins. To be published, . PubMed id: 37169960

Date:

24-Nov-22 Release date: 10-May-23

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 223 a.a.*

Protein chain

P54311  (GBB1_RAT) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Rattus norvegicus

Seq: 340 a.a.

Struc: 339 a.a.

Protein chain

Q16581  (C3AR_HUMAN) -  C3a anaphylatoxin chemotactic receptor from Homo sapiens

Seq: 482 a.a.

Struc: 284 a.a.

Protein chain

P63212  (GBG2_BOVIN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Bos taurus

Seq: 71 a.a.

Struc: 56 a.a.

Protein chain

No UniProt id for this chain

Struc: 233 a.a.

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????