PDBsum entry 8hij

Transport protein

PDB id: 8hij

Contents

Protein chains

498 a.a.

225 a.a.

120 a.a.

212 a.a.

Ligands

THH

PDB id:

8hij

Name:

Transport protein

Title:

The 5-mthf-bound bril-slc19a1/fab/nb ternary complex

Structure:

Bril-slc19a1 chimera. Chain: a. Engineered: yes. Anti-bril fab heavy chain. Chain: h. Engineered: yes. Anti-fab nanobody. Chain: n. Engineered: yes.

Source:

Escherichia coli, homo sapiens. Human. Organism_taxid: 562, 9606. Gene: cybc, slc19a1, flot1, rfc1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Homo sapiens. Organism_taxid: 9606. Lama glama.

Authors:

Z.Zhang,Y.Dang

Key ref:

Y.Dang et al. (2022). Molecular mechanism of substrate recognition by folat transporter slc19a1.. Cell discov, 8, 141. PubMed id: 36575193

Date:

20-Nov-22 Release date: 21-Dec-22

Protein chain

P0ABE7  (C562_ECOLX) -  Soluble cytochrome b562 from Escherichia coli

Seq: 128 a.a.

Struc: 498 a.a.*

Protein chain

P41440  (S19A1_HUMAN) -  Reduced folate transporter from Homo sapiens

Seq: 591 a.a.

Struc: 498 a.a.*

Protein chain

No UniProt id for this chain

Struc: 225 a.a.

Protein chain

No UniProt id for this chain

Struc: 120 a.a.

Protein chain

No UniProt id for this chain

Struc: 212 a.a.

* PDB and UniProt seqs differ at 24 residue positions (black crosses)