PDBsum entry 8hgf

Transferase

PDB id: 8hgf

Contents

Protein chains

508 a.a.

414 a.a.

PDB id:

8hgf

Name:

Transferase

Title:

Human pkm2 mutant - c326s

Structure:

Pyruvate kinase pkm. Chain: a, b, d, c. Synonym: cytosolic thyroid hormone-binding protein,cthbp,opa- interacting protein 3,oip-3,pyruvate kinase 2/3,pyruvate kinase muscle isozyme,threonine-protein kinase pkm2,thyroid hormone-binding protein 1,thbp1,tumor m2-pk,tyrosine-protein kinase pkm2,p58. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: pkm, oip3, pk2, pk3, pkm2. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

3.10Å R-factor: 0.184 R-free: 0.237

Authors:

Y.-C.Chen,K.-T.Lin,H.-C.Cheng

Key ref:

Y.-C.Chen et al. Human pkm2 mutant - C326s. To be published, .

Date:

14-Nov-22 Release date: 15-Nov-23

Protein chains

P14618  (KPYM_HUMAN) -  Pyruvate kinase PKM from Homo sapiens

Seq: 531 a.a.

Struc: 508 a.a.*

Protein chain

P14618  (KPYM_HUMAN) -  Pyruvate kinase PKM from Homo sapiens

Seq: 531 a.a.

Struc: 414 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)