PDBsum entry 8hg7

Transport protein

PDB id: 8hg7

Contents

Protein chains

590 a.a.

29 a.a.

Ligands

NAG

LFL

Metals

_NA

Waters ×2

PDB id:

8hg7

Name:

Transport protein

Title:

Structure of human sglt2-map17 complex with sotagliflozin

Structure:

Sodium/glucose cotransporter 2. Chain: a. Synonym: na(+)/glucose cotransporter 2,low affinity sodium-glucose cotransporter,solute carrier family 5 member 2. Engineered: yes. Pdzk1-interacting protein 1. Chain: b. Synonym: 17 kda membrane-associated protein. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: slc5a2, sglt2. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: map17. Expression_system_taxid: 9606

Authors:

M.Hiraizumi,H.Kishida,I.Miyaguchi,O.Nureki

Key ref:

M.Hiraizumi et al. Structural basis of glucose transport by the human sglt2-Map17 glucose transporter. To be published, . PubMed id: 38057552

Date:

14-Nov-22 Release date: 15-Nov-23

Protein chain

P31639  (SC5A2_HUMAN) -  Sodium/glucose cotransporter 2 from Homo sapiens

Seq: 672 a.a.

Struc: 590 a.a.

Protein chain

Q13113  (PDZ1I_HUMAN) -  PDZK1-interacting protein 1 from Homo sapiens

Seq: 114 a.a.

Struc: 29 a.a.