PDBsum entry 8hg0

Viral protein

PDB id: 8hg0

Contents

Protein chains

595 a.a.

195 a.a.

Ligands

NAG ×3

Metals

_ZN

PDB id:

8hg0

Name:

Viral protein

Title:

Cryo-em structure of sars-cov-2 prototype spike protein receptor- binding domain in complex with white-tailed deer ace2

Structure:

Angiotensin-converting enzyme. Chain: a. Engineered: yes. Spike protein s1. Chain: b. Synonym: s glycoprotein,e2,peplomer protein. Engineered: yes

Source:

Odocoileus virginianus texanus. Organism_taxid: 9880. Gene: ace2. Expressed in: homo sapiens. Expression_system_taxid: 9606. Severe acute respiratory syndrome coronavirus 2. 2019-ncov, sars-cov-2. Organism_taxid: 2697049.

Authors:

P.Han,Y.M.Meng,J.X.Qi

Key ref:

P.Han et al. Structural basis of sars-Cov-2 binding to ace 2 recep white-Tailed deer, Odocoileus virginianus. To be published, . PubMed id: 37676003

Date:

13-Nov-22 Release date: 30-Aug-23

Protein chain

A0A6J0Z472  (A0A6J0Z472_ODOVR) -  Angiotensin-converting enzyme from Odocoileus virginianus texanus

Seq: 679 a.a.

Struc: 595 a.a.

Protein chain

P0DTC2  (SPIKE_SARS2) -  Spike glycoprotein from Severe acute respiratory syndrome coronavirus 2

Seq: 1273 a.a.

Struc: 195 a.a.

Enzyme reactions

• Enzyme class 1: Chain A: E.C.3.4.-.-
• Enzyme class 2: Chain A: E.C.3.4.17.23 - angiotensin-converting enzyme 2.
• Reaction: angiotensin II + H2O = angiotensin-^1-7 + L-phenylalanine

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site