PDBsum entry 8hfc

Transferase

PDB id: 8hfc

Contents

Protein chains

276 a.a.

222 a.a.

Ligands

PLM

Metals

_ZN ×2

PDB id:

8hfc

Name:

Transferase

Title:

Cryo-em structure of yeast erf2/erf4 complex

Structure:

Palmitoyltransferase erf2. Chain: a. Synonym: dhhc cysteine-rich domain-containing protein erf2,ras protein acyltransferase. Engineered: yes. Ras modification protein erf4. Chain: b. Synonym: hyperactive ras suppressor protein 5. Engineered: yes

Source:

Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Gene: erf2, ylr246w. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: shr5, erf4, yol110w, hrc237. Expression_system_taxid: 7108

Authors:

J.Wu,Q.Hu,Y.Zhang,A.Yang,S.Liu

Key ref:

J.Wu et al. Cryo-Em structure of yeast erf2/erf4 complex. To be published, . PubMed id: 38182928

Date:

10-Nov-22 Release date: 22-Nov-23

Protein chain

Q06551  (ERFB_YEAST) -  Palmitoyltransferase ERF2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Seq: 359 a.a.

Struc: 276 a.a.

Protein chain

P41912  (ERFD_YEAST) -  Ras modification protein ERF4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Seq: 237 a.a.

Struc: 222 a.a.

Enzyme reactions

• Enzyme class: Chain A: E.C.2.3.1.225 - protein S-acyltransferase.
• Reaction: L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl- [protein] + CoA

Molecule diagrams generated from .mol files obtained from the KEGG ftp site