PDBsum entry 8hc7

Viral protein/immune system

PDB id: 8hc7

Contents

Protein chains

430 a.a.

267 a.a.

115 a.a.

107 a.a.

Ligands

NAG ×7

PDB id:

8hc7

Name:

Viral protein/immune system

Title:

Sars-cov-2 omicron ba.1 spike trimer (6p) complex with yb9-258 fab, focused refinement of rbd-dimer region

Structure:

Spike protein s1. Chain: c. Engineered: yes. Spike protein s1. Chain: a. Engineered: yes. Heavy chain variable region of yb9-258. Chain: h. Engineered: yes.

Source:

Severe acute respiratory syndrome coronavirus 2. 2019-ncov, sars-cov-2. Organism_taxid: 2697049. Gene: s, 2. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293. Homo sapiens.

Authors:

B.Liu,X.Gao,Q.Chen,Z.Li,M.Su,J.He,X.Xiong

Key ref:

H.Yu et al. Sars-Cov-2 breakthrough infections induce somatically hypermutated broadly neutralizing antibodies against heterologous variants. To be published, . PubMed id: 36828833

Date:

01-Nov-22 Release date: 25-Jan-23

Protein chain

P0DTC2  (SPIKE_SARS2) -  Spike glycoprotein from Severe acute respiratory syndrome coronavirus 2

Seq: 1273 a.a.

Struc: 430 a.a.*

Protein chain

P0DTC2  (SPIKE_SARS2) -  Spike glycoprotein from Severe acute respiratory syndrome coronavirus 2

Seq: 1273 a.a.

Struc: 267 a.a.*

Protein chain

No UniProt id for this chain

Struc: 115 a.a.

Protein chain

No UniProt id for this chain

Struc: 107 a.a.

* PDB and UniProt seqs differ at 34 residue positions (black crosses)