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PDBsum entry 8hc6

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protein ligands Protein-protein interface(s) links
Viral protein/immune system PDB id
8hc6

 

 

 

 

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Contents
Protein chains
267 a.a.
214 a.a.
215 a.a.
237 a.a.
Ligands
NAG ×7
PDB id:
8hc6
Name: Viral protein/immune system
Title: Sars-cov-2 omicron ba.1 spike trimer (6p) in complex with yb9-258 fab, focused refinement of fab region
Structure: Spike protein s1. Chain: c. Engineered: yes. Heavy chain of yb9-258 fab. Chain: h. Engineered: yes. Light chain of yb9-258. Chain: l. Engineered: yes.
Source: Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Gene: s, 2. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293. Homo sapiens. Organism_taxid: 9606.
Authors: B.Liu,X.Gao,Q.Chen,Z.Li,M.Su,J.He,X.Xiong
Key ref: H.Yu et al. Sars-Cov-2 breakthrough infections induce somatically hypermutated broadly neutralizing antibodies against heterologous variants. To be published, . PubMed id: 36828833
Date:
01-Nov-22     Release date:   25-Jan-23    
PROCHECK
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 Headers
 References

Protein chain
P0DTC2  (SPIKE_SARS2) -  Spike glycoprotein from Severe acute respiratory syndrome coronavirus 2
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1273 a.a.
267 a.a.*
Protein chain
No UniProt id for this chain
Struc: 214 a.a.
Protein chain
No UniProt id for this chain
Struc: 215 a.a.
Protein chain
P0DTC2  (SPIKE_SARS2) -  Spike glycoprotein from Severe acute respiratory syndrome coronavirus 2
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1273 a.a.
237 a.a.*
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 19 residue positions (black crosses)

 

 

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