PDBsum entry 8hb5

Immune system

PDB id: 8hb5

Contents

Protein chain

146 a.a.

Ligands

L6N

Metals

_CA ×3

Waters ×3

PDB id:

8hb5

Name:

Immune system

Title:

Crystal structure of mincle in complex with hd-275

Structure:

C-type lectin domain family 4 member e. Chain: a. Engineered: yes. Mutation: yes

Source:

Bos taurus. Cattle. Organism_taxid: 9913. Gene: clec4e. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.60Å R-factor: 0.298 R-free: 0.336

Authors:

S.Ishizuka,M.Nagae,S.Yamasaki

Key ref:

S.Ishizuka et al. (2023). Pgl-Iii, A rare intermediate of mycobacterium leprae phenolic glycolipid biosynthesis, Is a potent mincle. Acs cent sci, 9, 1388. PubMed id: 37521780

Date:

27-Oct-22 Release date: 09-Aug-23

Protein chain

E1BHM0  (E1BHM0_BOVIN) -  C-type lectin domain family 4 member E from Bos taurus

Seq: 211 a.a.

Struc: 146 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)