PDBsum entry 8h5t

Viral protein

PDB id: 8h5t

Contents

Protein chains

186 a.a.

119 a.a.

Ligands

NAG

Waters ×146

PDB id:

8h5t

Name:

Viral protein

Title:

Crystal structure of sars-cov-2 spike receptor-binding domain in complex with neutralizing nanobody nb-015

Structure:

Spike protein s1. Chain: a. Engineered: yes. Nanobody nb-015. Chain: b. Engineered: yes

Source:

Severe acute respiratory syndrome coronavirus 2. 2019-ncov, sars-cov-2. Organism_taxid: 2697049. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Vicugna pacos. Organism_taxid: 30538. Expressed in: brevibacillus choshinensis.

Resolution:

2.00Å R-factor: 0.173 R-free: 0.205

Authors:

J.Yang,S.Lin,G.W.Lu

Key ref:

J.Yang et al. Development of a bispecific nanobody conjugate broadl neutralizes circulating sars-Cov-2 variants and struc basis for its broad neutralization. To be published, . PubMed id: 38033141

Date:

13-Oct-22 Release date: 18-Oct-23

Protein chain

P0DTC2  (SPIKE_SARS2) -  Spike glycoprotein from Severe acute respiratory syndrome coronavirus 2

Seq: 1273 a.a.

Struc: 186 a.a.

Protein chain

No UniProt id for this chain

Struc: 119 a.a.