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PDBsum entry 8h1q
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PDB id:
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Transferase
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Title:
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Serine palmitoyltransferase from sphingobacterium multivorum complexed with l-serine
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Structure:
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Serine palmitoyltransferase. Chain: a. Synonym: spt. Engineered: yes
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Source:
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Sphingobacterium multivorum. Organism_taxid: 28454. Gene: spt, i6j33_20140, nctc11343_02561, sphingo8bc_150128. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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1.50Å
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R-factor:
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0.148
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R-free:
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0.184
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Authors:
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T.Murakami,A.Takahashi,A.Katayama,I.Miyahara,N.Kamiya,H.Ikushiro, T.Yano
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Key ref:
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H.Ikushiro
et al.
(2023).
Structural insights into the substrate recognition of palmitoyltransferase from sphingobacterium multivorum.
J.Biol.Chem.,
299,
04684.
PubMed id:
DOI:
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Date:
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03-Oct-22
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Release date:
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16-Aug-23
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PROCHECK
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Headers
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References
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A7BFV6
(A7BFV6_SPHMU) -
Serine palmitoyltransferase from Sphingobacterium multivorum
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Seq:
Struc:
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399 a.a.
394 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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Enzyme class:
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E.C.2.3.1.50
- serine C-palmitoyltransferase.
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Reaction:
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L-serine + hexadecanoyl-CoA + H+ = 3-oxosphinganine + CO2 + CoA
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L-serine
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+
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hexadecanoyl-CoA
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+
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H(+)
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=
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3-oxosphinganine
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+
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CO2
Bound ligand (Het Group name = )
matches with 40.00% similarity
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+
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CoA
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Cofactor:
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Pyridoxal 5'-phosphate
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Pyridoxal 5'-phosphate
Bound ligand (Het Group name =
PLS)
matches with 65.22% similarity
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
