PDBsum entry 8gpy

Viral protein

PDB id: 8gpy

Contents

Protein chains

191 a.a.

180 a.a.

227 a.a.

Waters ×149

PDB id:

8gpy

Name:

Viral protein

Title:

Crystal structure of omicron ba.4/5 rbd in complex with a neutralizing antibody scfv

Structure:

Spike protein s1. Chain: a, b. Engineered: yes. Scfv. Chain: c, e. Engineered: yes

Source:

Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Gene: s, 2. Expressed in: trichoplusia. Expression_system_taxid: 7110. Homo sapiens. Organism_taxid: 9606. Expression_system_taxid: 7110

Resolution:

2.51Å R-factor: 0.217 R-free: 0.251

Authors:

Y.X.Gao,Z.D.Song,W.M.Wang,Y.Guo

Key ref:

Y.Guo et al. (2023). Discovery and characterization of potent pan-Variant sars-Cov-2 neutralizing antibodies from individuals w omicron breakthrough infection.. Nat commun, 14, 3537. PubMed id: 37322000

Date:

27-Aug-22 Release date: 28-Jun-23

Protein chain

P0DTC2  (SPIKE_SARS2) -  Spike glycoprotein from Severe acute respiratory syndrome coronavirus 2

Seq: 1273 a.a.

Struc: 191 a.a.*

Protein chain

P0DTC2  (SPIKE_SARS2) -  Spike glycoprotein from Severe acute respiratory syndrome coronavirus 2

Seq: 1273 a.a.

Struc: 180 a.a.*

Protein chains

No UniProt id for this chain

Struc: 227 a.a.

* PDB and UniProt seqs differ at 32 residue positions (black crosses)