PDBsum entry 8glg

Immune system

PDB id: 8glg

Contents

Protein chains

280 a.a.

100 a.a.

Ligands

NAG-NAG-BMA-MAN-MAN-FUC-FUC

NAG-FUC-NAG-FUC

L9Q

CUY

EDO ×4

Metals

_NI

_CL ×4

IOD ×2

Waters ×541

PDB id:

8glg

Name:

Immune system

Title:

Crystal structure of human cd1b in complex with phosphatidylethanolamine c34:1

Structure:

T-cell surface glycoprotein cd1b. Chain: a. Engineered: yes. Beta-2-microglobulin. Chain: b. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: cd1b. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: hi5. Gene: b2m, cdabp0092, hdcma22p.

Resolution:

1.60Å R-factor: 0.187 R-free: 0.209

Authors:

A.Shahine

Key ref:

S.Huang et al. (2023). Cd1 lipidomes reveal lipid-Binding motifs and size-Ba antigen-Display mechanisms. Cell(cambridge,Mass ), 186, 1. PubMed id: 37725977

Date:

22-Mar-23 Release date: 20-Sep-23

Protein chain

P29016  (CD1B_HUMAN) -  T-cell surface glycoprotein CD1b from Homo sapiens

Seq: 333 a.a.

Struc: 280 a.a.*

Protein chain

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 100 a.a.*

* PDB and UniProt seqs differ at 7 residue positions (black crosses)